The Effect of Several Commonly Used Antipsychotic Drugs on the Renal Function of Patients with Mental Illness

Objective: To understand the effects of several commonly used antipsychotics on renal function patients with mental illness. Method: Collected illness who were hospitalized in our hospital from January 2020 to June 2021, and selected as research subjects psychiatric disorders treated 2 kinds antipsychotic drugs; collected 3 ml venous blood before treatment one month after for tests; observed changes indexes treatment. Results: In 694 illness, using drugs, BUN: 4.42 ± 1.92 mmol/l; Cr: 70.97 16.92 μmol/l; CCr: 88.37 21.07 ml/min; β2-MG: 1.67 0.61 mg/L; UA: 359.90 112.82 CYS-C: 0.92 0.24 mg/L. One antipsychotics, 3.77 1.37 70.46 16.71 87.78 20.63 1.75 0.64 332.53 91.48 umol/l; urea nitrogen, β2 microglobulin, uric acid other items all changed significantly. The differences statistically significant, P < 0.01. Conclusion: Several drugs have a greater impact During treatment, should be monitored regularly, if severe damage is found, plan or dosage adjusted time avoid endangering life.